Truman, a high school English teacher, wakes up anxious, as always, and leaves for work. The effects of Truman’s mental health are portrayed through his relationship with the anthropomorphic representation of his mental illness embodied by a character called Her. Just down the street, Isla, an artist, moves into the attic above her grandmother, Gail’s, flower shop, to help Gail run the shop in her old age, while hoping to rekindle the spark she once had for her art. Truman and Isla face trigger after trigger as Isla struggles to find her purpose, leading her to question whether or not she should continue pursuing art, while Truman questions what he knows about his family and his own existence altogether.

With Gail’s encouragement, Isla begins to explore the community around her and rediscovers her creative spark. Meanwhile, Truman reconnects with his estranged father who helps him discover how his community, students, and family can impact him while he learns to live with Her.

Truman and Isla connect after Gail’s death, and the two find support in each other as they look to continue Gail’s colorful legacy. Truman and Isla learn to confide in each other and agree to be each other's shoulders to lean on.